Multiple Sclerosis Patients and Disease Modifying Therapies: Impact on Immune Responses against COVID-19 and SARS-CoV-2 Vaccination

被引:15
|
作者
Golshani, Maryam [1 ]
Hrdy, Jiri [1 ]
机构
[1] Charles Univ Prague, Fac Med, Inst Immunol & Microbiol, Prague 12800, Czech Republic
关键词
SARS-CoV-2; COVID-19; multiple sclerosis; DMTs; immunosuppression; vaccine; EFFICACY;
D O I
10.3390/vaccines10020279
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This article reviews the literature on SARS-CoV-2 pandemic and multiple sclerosis (MS). The first part of the paper focuses on the current data on immunopathology of SARS-CoV-2 and leading vaccines produced against COVID-19 infection. In the second part of the article, we discuss the effect of Disease Modifying Therapies (DMTs) on COVID-19 infection severity or SARS-CoV-2 vaccination in MS patients plus safety profile of different vaccine platforms in MS patients.
引用
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页数:18
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