A Novel Phytotoxic Nonenolide from Phomopsis sp HCCB03520

被引：18
|
作者：
Yang, Zhijun [1 ]
Ge, Mei [2 ]
Yin, Yu [2 ]
Chen, Yi [3 ]
Luo, Minyu [2 ]
Chen, Daijie [1 ]
机构：
[1] Shanghai Inst Pharmaceut Ind, Shanghai 200040, Peoples R China
[2] Shanghai Laiyi Ctr Biopharmaceut R&D, Shanghai 200240, Peoples R China
[3] Shanghai Normal Univ, Coll Life & Environm Sci, Shanghai 200234, Peoples R China
来源：
CHEMISTRY & BIODIVERSITY | 2012年 / 9卷 / 02期
关键词：
Nonenolide; Phomopsis sp; HCCB03520; Phytotoxic activity; Fungi; Lactones; METABOLITES; PRODUCTS; FUNGI;
D O I：
10.1002/cbdv.201100080
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A novel phytotoxic nonenolide, (6S,7R,9R)-6,7-dihydroxy-9-propylnon-4-eno-9-lactone (1), was isolated from solid cultures of the endophytic fungus Phomopsis sp. HCCB03520, together with three known compounds, cytochalasin H (2), cytochalasin N (3), and epoxycytochalasin H (4). The structures of these compounds were elucidated through spectroscopic analysis, and the absolute configurations were determined by CD spectroscopy. Phytotoxic activities of compounds 14 were also investigated. Compound 1 showed phytotoxic activity on germination and radicle growth of Medicago sativa, Trifolium hybridum, and Buchloe dactyloides.
引用
收藏
页码：403 / 408
页数：6
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