COMP 392-Using homology models and structure-based design to improve the MAO-A safety profile of oxazolidinone antibacterials

被引：0
|
作者：
Eyermann, C. [1 ]
Fleming, P. [1 ]
Gravestock, M. [1 ]
Jones, T. [2 ]
Kern, G. [1 ]
Ramsay, R. [2 ]
Reck, F. [1 ]
Zhou, F. [1 ]
机构：
[1] R&D Boston Inc, AstraZeneca, Infect Discovery Canc & Infect Res Area, Waltham, MA 02451 USA
[2] Univ St Andrews, St Andrews KY16 9ST, Fife, Scotland
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 234卷
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D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
392-COMP
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页数：1
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    Gilson, M. K.
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    [J]. THESCIENTIFICWORLDJOURNAL, 2006, 6 : 1542 - 1554
  • [2] High quality homology models for structure-based drug design: A comparative study.
    Nayeem, A
    Sitkoff, D
    Krystek, S
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2004, 228 : U536 - U536
  • [3] Synthesis and pharmacological evaluation of selective MAO-A inhibitors using structure and pharmacophore-based drug design
    Vijayalakshmi, M. K.
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    Vadivelan, S.
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    Magesh, M.
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    RING, CS
    SUN, E
    MCKERROW, JH
    LEE, GK
    ROSENTHAL, PJ
    KUNTZ, ID
    COHEN, FE
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) : 3583 - 3587
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