Conjugation of Carbohydrates with Quinolines: A Powerful Synthetic Tool

被引:2
|
作者
Simonetti, Sebastian O. [1 ,2 ]
Kaufman, Teodoro S. [1 ,2 ]
Larghi, Enrique L. [1 ,2 ]
机构
[1] Univ Nacl Rosario UNR, UNR, CONICET, Inst Quim Rosario IQUIR, Suipacha 531, RA-2000 Rosario, Argentina
[2] Univ Nacl Rosario UNR, Fac Ciencias Bioquim & Farmaceut, Suipacha 531, RA-2000 Rosario, Argentina
关键词
Carbohydrates; Glycosides; Glycosylation; Quinolines; Synthetic methods; XANTHURENIC ACID 8-O-BETA-D-GLUCOSIDE; ANTIOXIDANT MODULATORS; BIOLOGICAL EVALUATION; CONVERGENT SYNTHESIS; NATURAL-PRODUCTS; DERIVATIVES; NUCLEOSIDES; ALKALOIDS; GLYCOSYLATION; INHIBITORS;
D O I
10.1002/ejoc.202200107
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A detailed revision on natural and synthetic glycosylated quinolines, spanning the last 20 years, is presented. Exhaustive descriptions about the state of the art of the synthesis and relevant applications of these glyco-heterocycles are provided. In addition, an account of the natural products containing this motif and their associated bioactivity data are also outlined. For the sake of consistency, quinolones are also covered as well as hybrid compounds, embodied with linkers between the heterocyclic ring and the carbohydrate fragment.
引用
收藏
页数:30
相关论文
共 50 条
  • [1] Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination
    Di Wu
    Peng Xu
    Meagan Kelly
    Edward T. Ryan
    Pavol Kováč
    Grzegorz Piszczek
    Glycoconjugate Journal, 2023, 40 : 401 - 412
  • [2] Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination
    Wu, Di
    Xu, Peng
    Kelly, Meagan
    Ryan, Edward T. T.
    Kovac, Pavol
    Piszczek, Grzegorz
    GLYCOCONJUGATE JOURNAL, 2023, 40 (04) : 401 - 412
  • [3] HYDROBORATION - A POWERFUL SYNTHETIC TOOL
    BROWN, HC
    TETRAHEDRON, 1961, 12 (03) : 117 - &
  • [4] Mesitylcopper - A Powerful Tool in Synthetic Chemistry
    Stollenz, Michael
    Meyer, Franc
    ORGANOMETALLICS, 2012, 31 (22) : 7708 - 7727
  • [5] Directed evolution as a powerful synthetic biology tool
    Cobb, Ryan E.
    Sun, Ning
    Zhao, Huimin
    METHODS, 2013, 60 (01) : 81 - 90
  • [6] Enhancement of the immunogenicity of synthetic carbohydrates by conjugation to virosomes: A leishmaniasis vaccine candidate
    Liu, Xinyu
    Siegrist, Sibylle
    Amacker, Mario
    Zurbriggen, Rinaldo
    Pluschke, Gerd
    Seeberger, Peter H.
    ACS CHEMICAL BIOLOGY, 2006, 1 (03) : 161 - 164
  • [7] Protein Splicing of Inteins: A Powerful Tool in Synthetic Biology
    Wang, Hao
    Wang, Lin
    Zhong, Baihua
    Dai, Zhuojun
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 10
  • [8] CYCLOPROPANATION OF SILYL ENOL ETHERS - POWERFUL SYNTHETIC TOOL
    CONIA, JM
    PURE AND APPLIED CHEMISTRY, 1975, 43 (3-4) : 317 - 326
  • [9] Trans-kingdom conjugation offers a powerful gene targeting tool in yeast
    Nishikawa, M
    Yoshida, K
    GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING, 1998, 14 (03): : 65 - 73
  • [10] Pd asymmetric allylic alkylation (AAA). A powerful synthetic tool
    Trost, BM
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (01) : 1 - 14