Left Atrial Strain as a Predictor of Left Ventricular Diastolic Dysfunction in Patients with Arterial Hypertension
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作者:
Miljkovic, Tatjana
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Miljkovic, Tatjana
[1
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Ilic, Aleksandra
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Ilic, Aleksandra
[1
,2
]
Milovancev, Aleksandra
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Milovancev, Aleksandra
[1
,2
]
Bjelobrk, Marija
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Bjelobrk, Marija
[1
,2
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Stefanovic, Maja
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Stefanovic, Maja
[1
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Stojsic-Milosavljevic, Anastazija
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Stojsic-Milosavljevic, Anastazija
[1
,2
]
Tadic, Snezana
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Tadic, Snezana
[1
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Golubovic, Miodrag
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Golubovic, Miodrag
[1
,2
]
Popov, Tanja
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Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, SerbiaUniv Novi Sad, Fac Med, Novi Sad 21000, Serbia
Popov, Tanja
[1
,2
]
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Petrovic, Milovan
[1
,2
]
机构:
[1] Univ Novi Sad, Fac Med, Novi Sad 21000, Serbia
[2] Inst Cardiovasc Dis Vojvodina, Sremska Kamenica 21208, Serbia
Background and Objectives: There is emerging evidence of the usefulness of left atrial strain (LAS) in the assessment of diastolic dysfunction (DD). In this study we assess the sensitivity and specificity of LAS, to determine cut-off values and their association to DD with increased left atrial pressure (LAP) in patients with well-treated arterial hypertension. Materials and Methods: We performed a cross-sectional study on 180 subjects with well-treated arterial hypertension. All patients underwent transthoracic echocardiography. Patients were divided into two groups: a group without increased LAP and/or DD and a group with increased LAP DD. Results: In multivariate logistic regression, LAS proved to be the strongest statistically significant predictor of DD with increased LAP (OR 0.834, p < 0.0005), with AUC 0.885 and a set cut-off value of 24.27% with high sensitivity of 78.9% and specificity of 84.6%. The set cut-off for LAS > 24.27% was significantly highly prevalent in the group of DD with increased LAP 78.9% when compared to the group without increased LAP 15.4%, p < 0.0001. Conclusion: The findings of this study suggest that LAS could be a useful and highly sensitive and specific marker in the evaluation of DD. There is the potential for using LAS in everyday practice as a standard parameter in diastolic function assessment.
机构:
Tver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, RussiaTver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, Russia
Mazur, E. S.
Mazur, V. V.
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Tver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, RussiaTver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, Russia
Mazur, V. V.
Bazhenov, N. D.
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Tver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, RussiaTver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, Russia
Bazhenov, N. D.
Nilova, O. V.
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Tver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, RussiaTver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, Russia
Nilova, O. V.
Nikolayeva, T. O.
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Tver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, RussiaTver State Med Univ, Minist Hlth Russia, Fed State Budgetary Educ Inst Higher Educ, Tver, Russia