Constraint loss adjustments, based on finite element (FE) stress analysis and local critical stress, sigma', critical stressed volume, V', cleavage criteria were applied to fracture toughness data from small pre-cracked bend bars of the IEA heat of F82H irradiated to 6.6 dpa at 300 degrees C in the High Flux Isotope Reactor. The 100 MPa root m master curve method reference temperature shifts were evaluated based on both the measured toughness (Delta T-m) and after size-adjusting the toughness to small-scale yielding conditions at reference specimen size (Delta T-o) with values of approximate to 142 and 205 degrees C, respectively. The model based prediction Delta T-o = C-o Delta(sigma(fl)), where C-o approximate to 0.68 and Delta(sigma(fl)) is the change in the average flow stress over 0-10% strain is in excellent agreement with Delta T-o. The FE analyses also demonstrates an upper-bound K-Jc that can be measured with these small bend bars for irradiated alloys that suffer severe loss of strain hardening. (C) 2011 Published by Elsevier B.V.