Hypertrophic cardiomyopathy and ultra-endurance running - two incompatible entities?

被引：16

作者：

Wilson, Mathew G. ^{[2
]}

Chandra, Navin ^{[1
]}

Papadakis, Michael ^{[1
]}

O'Hanlon, Rory ^{[3
,4
]}

Prasad, Sanjay K. ^{[5
]}

Sharma, Sanjay ^{[1
]}

机构：

[1] St Georges Univ London, Div Cardiac & Vasc Sci, London, England

[2] Qatar Orthopaed & Sports Med Hosp, ASPETAR, Doha, Qatar

[3] St Vincents Univ Hosp, Dublin 4, Ireland

[4] Blackrock Clin, Dublin, Ireland

[5] Royal Brompton & Harefield NHS Trust, London, England

来源：

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE | 2011年 / 13卷

关键词：

Ultra-endurance exercise; hypertrophic cardiomyopathy; athlete?'?s heart; sudden cardiac death; pre-participation screening; CARDIOVASCULAR MAGNETIC-RESONANCE; PHYSIOLOGICAL CARDIAC-HYPERTROPHY; LEFT-VENTRICULAR HYPERTROPHY; SUDDEN-DEATH; MYOCARDIAL FIBROSIS; ELECTROCARDIOGRAPHIC PATTERNS; CLINICAL-SIGNIFICANCE; PERICARDIAL DISEASES; COMPETITIVE SPORTS; ETHNIC-DIFFERENCES;

D O I：

10.1186/1532-429X-13-77

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Regular and prolonged exercise is associated with increased left ventricular wall thickness that can overlap with hypertrophic cardiomyopathy (HCM). Differentiating physiological from pathological hypertrophy has important implications, since HCM is the commonest cause of exercise-related sudden cardiac death in young individuals. Most deaths have been reported in intermittent 'start-stop' sports such as football (soccer) and basketball. The theory is that individuals with HCM are unable to augment stroke volume sufficiently to meet the demands of endurance sports and are accordingly 'selected-out' of participation in such events. We report the case of an ultra-endurance athlete with 25 years of > 50 km competitive running experience, with genetically confirmed HCM; thereby demonstrating that these can be two compatible entities.

引用

页数：9

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