Detection of endogenous receptor modulation by a cAMP bio-sensor assay suitable for ultra-high-throughput screening

被引：0
|
作者：
Johnson, Eric N. [1 ]
机构：
[1] Merck & Co Inc, Dept Automated Biotechnol, Whitehouse Stn, NJ USA
来源：
JOURNAL OF BIOMOLECULAR SCREENING | 2008年 / 13卷 / 07期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：696 / 696
页数：1
相关论文
共 19 条
  • [1] HTS and assay miniaturization - Ultra-high-throughput screening comes of age
    Liszewski, K
    GENETIC ENGINEERING NEWS, 1998, 18 (20): : 9 - +
  • [2] Flow cytometry-based ultra-high-throughput screening assay for cellulase activity
    Ostafe, Raluca
    Prodanovic, Radivoje
    Commandeur, Ulrich
    Fischer, Rainer
    ANALYTICAL BIOCHEMISTRY, 2013, 435 (01) : 93 - 98
  • [3] Challenges and solutions to ultra-high-throughput screening assay miniaturization: submicroliter fluid handling
    Dunn, DA
    Feygin, I
    DRUG DISCOVERY TODAY, 2000, 5 (12) : S84 - S91
  • [4] A fluorescence-based thiol quantification assay for ultra-high-throughput screening for inhibitors of coenzyme A production
    Chung, Christine C.
    Ohwaki, Kenji
    Schneeweis, Jonathan E.
    Stec, Erica
    Varnerin, Jeffrey P.
    Goudreau, Paul N.
    Chang, Amy
    Cassaday, Jason
    Yang, Lihu
    Yamakawa, Takeru
    Kornienko, Oleg
    Hodder, Peter
    Inglese, James
    Ferrer, Marc
    Strulovici, Berta
    Kusunoki, Jun
    Tota, Michael R.
    Takagi, Toshimitsu
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2008, 6 (03) : 361 - 374
  • [5] A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase
    Brandish, Philip E.
    Chiu, Chi-Sung
    Schneeweis, Jonathan
    Brandon, Nicholas J.
    Leech, Clare L.
    Kornienko, Oleg
    Scolnick, Edward M.
    Strulovici, Berta
    Zheng, Wei
    JOURNAL OF BIOMOLECULAR SCREENING, 2006, 11 (05) : 481 - 487
  • [6] A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway
    Wunder, F
    Stasch, JP
    Hütter, J
    Alonso-Alija, C
    Hüser, J
    Lohrmann, E
    ANALYTICAL BIOCHEMISTRY, 2005, 339 (01) : 104 - 112
  • [7] Ultra-high-throughput screening for antagonists of a Gi-coupled receptor in a 2.2-μ1 3,456-well plate format CyclicAMP assay
    Weber, Michael
    Muthusubramaniam, Lalitha
    Murray, Justin
    Hudak, Ed
    Kornienko, Oleg
    Johnson, Eric N.
    Strulovici, Berta
    Kunapuli, Priya
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2007, 5 (01) : 117 - 125
  • [8] Screening of HIV-1 Protease Using a Combination of an Ultra-High-Throughput Fluorescent-Based Assay and RapidFire Mass Spectrometry
    Meng, Juncai
    Lai, Ming-Tain
    Munshi, Vandna
    Grobler, Jay
    McCauley, John
    Zuck, Paul
    Johnson, Eric N.
    Uebele, Victor N.
    Hermes, Jeffrey D.
    Adam, Gregory C.
    JOURNAL OF BIOMOLECULAR SCREENING, 2015, 20 (05) : 606 - 615
  • [9] Hit Discovery for Public Target Programs in the European Lead Factory: Experiences and Output from Assay Development and Ultra-High-Throughput Screening
    Honarnejad, Saman
    van Boeckel, Stan
    van den Hurk, Helma
    van Helden, Steven
    SLAS DISCOVERY, 2021, 26 (02) : 192 - 204
  • [10] Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation
    Fernandez, Delia, I
    Provenzale, Isabella
    Cheung, Hilaire Y. F.
    van Groningen, Jan
    Tullemans, Bibian M. E.
    Veninga, Alicia
    Dunster, Joanne L.
    Honarnejad, Saman
    van den Hurk, Helma
    Kuijpers, Marijke J. E.
    Heemskerk, Johan W. M.
    ISCIENCE, 2022, 25 (01)
12