The evolution of sports participation guidelines and the influence of genotype-phenotype correlation in long QT syndrome

被引:4
|
作者
Furst, Matthew L. [1 ]
Aziz, Peter F. [1 ]
机构
[1] Cleveland Clin Fdn, Cleveland Clin Childrens, Dept Pediat Electrophysiol, 9500 Euclid Ave, Cleveland, OH 44195 USA
关键词
Long QT syndrome; Sports participation; Sports guidelines; Genotype-phenotype correlation; ABORTED CARDIAC-ARREST; TORSADE-DE-POINTES; RISK-FACTORS; EARLY AFTERDEPOLARIZATIONS; CARDIOVASCULAR-ABNORMALITIES; CELLULAR MECHANISMS; EUROPEAN-SOCIETY; CLINICAL-COURSE; I-KS; CHILDREN;
D O I
10.1016/j.tcm.2016.04.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Congenital Long QT Syndrome (LQTS) results in abnormal ventricular repolarization in patients with otherwise structurally normal hearts. Following the initial clinical descriptions of LQTS, there has been a great deal of investigation into the genetic etiology and pathophysiology of these entities, with the goal of improved screening tools and understanding of associated risks. Through this work, heart rhythm experts continue to revise their recommendations regarding sports eligibility. We review the evolution of sports participation recommendations for LQTS.
引用
收藏
页码:690 / 697
页数:8
相关论文
共 50 条
  • [1] Genotype-phenotype correlation in Scottish Long QT (Romano Ward syndrome) patients
    Brown, Catriona
    Walker, D.
    Kelly, K.
    Clark, C.
    Broadhurst, P.
    Choy, A-M
    Findlay, I.
    Goudie, D.
    Grieve, J.
    Grubb, N.
    Lam, W.
    Murday, V.
    Porteous, M.
    Pringle, T.
    Dean, J.
    [J]. JOURNAL OF MEDICAL GENETICS, 2008, 45 : S57 - S57
  • [2] Genotype-phenotype relationships in congenital long QT syndrome
    Ackerman, MJ
    [J]. JOURNAL OF ELECTROCARDIOLOGY, 2005, 38 (04) : 64 - 68
  • [4] Genotype-Phenotype Aspects of Type 2 Long QT Syndrome
    Shimizu, Wataru
    Moss, Arthur J.
    Wilde, Arthur A. M.
    Towbin, Jeffrey A.
    Ackerman, Michael J.
    January, Craig T.
    Tester, David J.
    Zareba, Wojciech
    Robinson, Jennifer L.
    Qi, Ming
    Vincent, G. Michael
    Kaufman, Elizabeth S.
    Hofman, Nynke
    Noda, Takashi
    Kamakura, Shiro
    Miyamoto, Yoshihiro
    Shah, Samit
    Amin, Vinit
    Goldenberg, Ilan
    Andrews, Mark L.
    McNitt, Scott
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (22) : 2052 - 2062
  • [5] The use of genotype-phenotype correlations in mutation analysis for the long QT syndrome
    Van Langen, IM
    Birnie, E
    Alders, M
    Jongbloed, RJ
    Le Marec, H
    Wilde, AAM
    [J]. JOURNAL OF MEDICAL GENETICS, 2003, 40 (02) : 141 - 145
  • [6] Short QT syndrome genotype-phenotype correlations
    不详
    [J]. JOURNAL OF ELECTROCARDIOLOGY, 2005, 38 (04) : 75 - 80
  • [7] Genotype-phenotype correlation of novel KV7.1 mutations identified in patients with Long QT syndrome
    Refaat, M.
    Bomholtz, S.
    Steffensen, A.
    David, J.
    Espinosa, K.
    Bentzen, B.
    Nussbaum, R.
    Wojciak, J.
    Scheinman, M.
    Schmitt, N.
    [J]. EUROPEAN HEART JOURNAL, 2017, 38 : 1241 - 1242
  • [8] Genotype-phenotype correlation in Marfan syndrome
    Child, AH
    Arahon-Martin, J
    Comeglio, P
    [J]. MATRIX BIOLOGY, 2004, 23 (06) : 396 - 397
  • [9] Genotype-phenotype correlation in Down syndrome
    Trivino, E
    Sierra, C
    Dolade, M
    Navarro, E
    Brandi, N
    Mira, A
    Cabre, E
    Martin, S
    Pastor, MC
    Crespo, M
    SeresSantamaria, A
    Gimenez, C
    [J]. CYTOGENETICS AND CELL GENETICS, 1997, 77 : 22 - 23
  • [10] Genotype-phenotype correlation in Apert syndrome
    Mcglaughlin, K.
    Anderson, P.
    Netherway, D.
    Roscioli, T.
    Yusof, A.
    Carney, B.
    Coxon, R.
    David, D.
    [J]. Craniofacial Surgery, 2005, : 297 - 299