Combined tubular adenocarcinoma and hepatoid adenocarcinoma arising in Barrett esophagus

被引：10
|
作者：
Kuroda, Naoto [1 ]
Onishi, Kazuhisa [2 ]
Lee, Gang-Hong [3 ]
机构：
[1] Kochi Univ, Kochi Red Cross Hosp, Dept Diagnost Pathol, Kochi 7808562, Japan
[2] Kochi Univ, Kochi Red Cross Hosp, Dept Surg, Kochi 7808562, Japan
[3] Kochi Univ, Kochi Med Sch, Dept Pathol, Kochi 7808562, Japan
来源：
ANNALS OF DIAGNOSTIC PATHOLOGY | 2011年 / 15卷 / 06期
关键词：
Hepatoid adenocarcinoma; Barrett esophagus; Intestinal metaplasia; COMBINED CHORIOCARCINOMA; STOMACH; HISTOGENESIS; PROGRESSION; ASSOCIATION; EXPRESSION;
D O I：
10.1016/j.anndiagpath.2010.06.006
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Hepatoid adenocarcinoma arising in the esophagus is extremely rare. To date, there are only 3 cases in the world English literature. We report the fourth case here. A 76-year-old Japanese man was admitted to our hospital because of the deterioration of nephritic syndrome. He presented with chest burn, and the endoscopic examination of upper digestive tract disclosed the tumor in the lower esophagus. The subtotal esophagectomy was undertaken because of esophageal cancer. The postoperative histologic examination showed the finding of combined tubular adenocarcinoma and hepatoid adenocarcinoma arising in Barrett esophagus. Immunohistochemically, hepatoid adenocarcinoma cells were positive for a-fetoprotein, hepatocyte, a1-antitrypsin, a1-antichymotrypsin, and CDX2, but negative for MUC5AC and MDC6. Esophageal hepatoid adenocarcinoma seems to be closely associated with Barrett esophagus and show the intestinal phenotype rather than gastric phenotype. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码：450 / 453
页数：4
相关论文
共 50 条
  • [1] Combined tubular adenocarcinoma and hepatoid adenocarcinoma arising barrett's esophagus
    Kuroda, N.
    HISTOPATHOLOGY, 2010, 57 : 85 - 85
  • [2] Combined tubular adenocarcinoma, neuroendocrine carcinoma and adenocarcinoma with enteroblastic differentiation arising in Barrett esophagus
    Kotaro Sugawara
    Takashi Fukuda
    Yutaka Kishimoto
    Daiji Oka
    Yoshiyuki Kawashima
    Naoko Inoshita
    Hiroaki Kanda
    Clinical Journal of Gastroenterology, 2023, 16 : 501 - 507
  • [3] Combined tubular adenocarcinoma, neuroendocrine carcinoma and adenocarcinoma with enteroblastic differentiation arising in Barrett esophagus
    Sugawara, Kotaro
    Fukuda, Takashi
    Kishimoto, Yutaka
    Oka, Daiji
    Kawashima, Yoshiyuki
    Inoshita, Naoko
    Kanda, Hiroaki
    CLINICAL JOURNAL OF GASTROENTEROLOGY, 2023, 16 (04) : 501 - 507
  • [4] Esophageal adenocarcinoma arising in Barrett esophagus
    Zhang, Hui Ying
    Spechler, Stuart Jon
    Souza, Rhonda F.
    CANCER LETTERS, 2009, 275 (02) : 170 - 177
  • [5] Prognosis of adenocarcinoma arising in Barrett's esophagus
    Hoff, SJ
    Sawyers, JL
    Blanke, CD
    Choy, H
    Stewart, JR
    ANNALS OF THORACIC SURGERY, 1998, 65 (01): : 176 - 180
  • [6] Combined choriocarcinoma, hepatoid adenocarcinoma, small cell carcinoma and tubular adenocarcinoma in the oesophagus
    Motoyama, T
    Higuchi, M
    Taguchi, J
    VIRCHOWS ARCHIV, 1995, 427 (04) : 451 - 454
  • [7] Molecular biology of adenocarcinoma arising in Barrett's esophagus
    Mueller, JD
    SUPERFICIAL ESOPHAGEAL NEOPLASM: PATHOLOGY, DIAGNOSIS, AND THERAPY, 2002, : 181 - 187
  • [8] Multiple polyposis and adenocarcinoma arising in Barrett's esophagus
    Wong, RS
    Temes, RT
    Follis, FM
    Kessler, RM
    Pett, SB
    Wernly, JA
    ANNALS OF THORACIC SURGERY, 1996, 61 (01): : 216 - 218
  • [9] ADENOCARCINOMA ARISING IN BARRETT ESOPHAGUS - PATHOLOGIC AND RADIOLOGIC FEATURES
    KEEN, SJ
    DODD, GD
    SMITH, JL
    MOUNT SINAI JOURNAL OF MEDICINE, 1984, 51 (04): : 442 - 450
  • [10] Hepatoid adenocarcinoma of the lower esophagus
    Sockeel, P
    Abbey-Toby, A
    Regimbeau, JM
    Cazals-Hatem, D
    Belghiti, J
    Sauvanet, A
    GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2004, 28 (01): : 84 - 86
12345