H5N1 influenza viruses: Facts, not fear

被引：46

作者：

Palese, Peter ^{[1
,2
]}

Wang, Taia T. ^{[1
]}

机构：

[1] Mt Sinai Sch Med, Dept Microbiol, New York, NY 10029 USA

[2] Mt Sinai Sch Med, Dept Med, New York, NY 10029 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2012年 / 109卷 / 07期

关键词：

avian influenza; moratorium; World Health Organization; case fatality rate; National Science Advisory Board for Biosecurity; H9N2 AVIAN INFLUENZA; RECEPTOR SPECIFICITY; A VIRUSES; POULTRY WORKERS; ANIMAL-MODELS; FERRET MODEL; IN-VITRO; TRANSMISSION; PATHOGENESIS; VACCINES;

D O I：

10.1073/pnas.1121297109

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The ongoing controversy over publication of two studies involving the transmission in ferrets of H5N1 (H5) subtype influenza viruses and the recommendations of the National Science Advisory Board for Biosecurity to redact key details in the manuscripts call for an examination of relevant scientific facts. In addition, there are calls in the media to destroy the viruses, curtail future research in this area, and protect the public from such "frightening" research efforts. Fear needs to be put to rest with solid science and not speculation.

引用

页码：2211 / 2213

页数：3

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Hay, A
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Klimov, A
Kwon, YK
Lee, CW
Lien, PS
Li, YB
Lim, W
Lin, YP
Lindstom, S
Loftin, L
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[7] Mechanisms of pathogenicity of influenza A (H5N1) viruses in mice
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