Infliximab-induced psoriasis during therapy for Crohn's disease

被引：16

作者：

Steinwurz, Flavio ^{[1
]}

Denadai, Rafael ^{[2
]}

Saad-Hossne, Rogerio ^{[3
]}

Queiroz, Maria Luiza

Teixeira, Fabio Vieira ^{[4
]}

Romiti, Ricardo ^{[5
]}

机构：

[1] Hosp Israelita Albert Einstein, Unit Inflammatory Bowel Dis, BR-05652900 Sao Paulo, Brazil

[2] Univ State Sao Paulo UNESP, Botucatu Med Sch, Dept Surg, Div Coloproctol, Botucatu, SP, Brazil

[3] State Univ Sao Paulo UNESP, Sch Med Sci, Dept Surg, Div Coloproctol, Botucatu, SP, Brazil

[4] Univ State Sao Paulo UNESP, Sch Med Sci, Dept Surg, Div Coloproctol, Botucatu, SP, Brazil

[5] Univ Sao Paulo, Sch Med Sci, Dept Dermatol, Sao Paulo, Brazil

来源：

JOURNAL OF CROHNS & COLITIS | 2012年 / 6卷 / 05期

关键词：

Biological therapy; Crohn's disease; Infliximab; Psoriasis; Tumor necrosis factor-alpha inhibitors; INFLAMMATORY-BOWEL-DISEASE; FACTOR-ALPHA THERAPY; FACTOR ANTAGONIST THERAPY; PUSTULAR PSORIASIS; FLEXURAL PSORIASIS; ADVERSE-REACTION; CASE SERIES; NEW-ONSET; NECROSIS; PATIENT;

D O I：

10.1016/j.crohns.2011.12.007

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Although therapy with tumor necrosis factor-alpha inhibitors (anti-TNF) provides beneficial effects in different immune inflammatory disorders, paradoxical cases of anti-THE-induced psoriasis have increasingly been reported, mostly in the setting of rheumatologic diseases. To date, less than 50 cases of infliximab-induced psoriasis in inflammatory bowel disease patients have been described. The present report was aimed at describing two new cases of infliximab-induced psoriasis during therapy for Crohn's disease and at carrying out a review on this intriguing phenomenon. (C) 2011 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.

引用

页码：610 / 616

页数：7

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