Ramipril reduces QT dispersion in patients with acute myocardial infarction and heart failure

被引：19
|
作者：
Spargias, KS [1 ]
Lindsay, SJ [1 ]
Hall, AS [1 ]
Cowan, JC [1 ]
Ball, SG [1 ]
机构：
[1] Univ Leeds, Inst Cardiovasc Res, Leeds LS2 9JT, W Yorkshire, England
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 83卷 / 06期
关键词：
D O I：
10.1016/S0002-9149(98)01049-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In a cohort of 67 patients from the Acute Infarction Ramipril Efficacy study, we showed that ramipril therapy was associated with a significant reduction in QT dispersion over a 2-month period after acute myocardial infarction. This reduction of ventricular repolarization inhomogeneity indicates an antiarrhythmic effect and may be an important additional mechanism for the reduced ah-cause mortality and sudden death incidence achieved with angiotensin-converting enzyme inhibition after acute myocardial infarction.
引用
收藏
页码：969 / +
页数：4
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