ANTIBODY LEVELS TO HANTAVIRUS IN INHABITANTS OF WESTERN SANTA CATARINA STATE, BRAZIL

被引:6
|
作者
de Souza, William Marciel [1 ]
Machado, Alex Martins [1 ]
Disner, Geonildo Rodrigo [2 ]
Boff, Everton [2 ]
da Silva Rodrigues Machado, Aline Rafaela [1 ]
de Padua, Michelly [1 ]
Moraes Figueiredo, Luiz Tadeu [1 ]
de Miranda, Gustavo Borba [2 ]
机构
[1] Univ Sao Paulo, Sch Med Ribeirao Preto, BR-14049900 Ribeirao Preto, SP, Brazil
[2] Univ Oeste Santa Catarina, Dept Biol Sci & Hlth, BR-89900000 Sao Miguel Do Oeste, SC, Brazil
基金
巴西圣保罗研究基金会;
关键词
Hantavirus; Epidemiology; Brazil; Argentina; Santa Catarina; PULMONARY SYNDROME; SEROLOGIC EVIDENCE; SOUTHERN BRAZIL; INFECTION; ARGENTINA; AMERICA; VIRUS; TRANSMISSION; EXPRESSION; PARAGUAY;
D O I
10.1590/S0036-46652012000400002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity), with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.
引用
收藏
页码:193 / 196
页数:4
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