Agriculture in India and other Asian countries is facing multiple and complex challenges which are expected to become more severe with the passage of time. Some of the major challenges are sustainability of natural resources, impact of climate change and decline in factor of productivity. Besides, the declining trend in size of land holding poses a serious challenge to the profitability and sustainability of farming. In view of the decline in per capita availability of land, it is imperative to develop strategies and agricultural technologies that enable adequate employment and income generation, especially for small-holders (farmers with < 2.0 ha of land) who constitute the vast majority of the farming community in the developing world. No single farm enterprise, such as a typical mono-cropping system, is likely to be able to sustain the small-holder farmer. Integrated farming systems (IFS) are less risky if managed efficiently, as they benefit from synergisms among enterprises, diversity in produce, and environmental soundness. On this basis, IFS have been suggested for the development of small and marginal farms across Asia, and researchers have developed strategies which have benefited small-holder farmers by providing additional income and employment and minimizing risk. However, these IFS have not been promulgated and promoted effectively. The present review helps to remedy this by providing comprehensive information on the concepts and advantages of IFS for small-holder farmers, which is lacking at present. The review covers the key literature on farming systems and allied aspects published over the period 1970-2015.