Tyrphostin AG490 inhibits IL-3-induced activation of JAK-STAT pathway in microglia

被引:0
|
作者
Natarajan, C [1 ]
Sriram, S [1 ]
Bright, JJ [1 ]
机构
[1] Vanderbilt Univ, Med Ctr, Nashville, TN 37212 USA
来源
FASEB JOURNAL | 2001年 / 15卷 / 05期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1213 / A1213
页数:1
相关论文
共 50 条
  • [1] Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts
    Kirken, RA
    Erwin-Cohen, R
    Behbod, F
    Wang, ME
    Stepkowski, SM
    Kahan, BD
    [J]. TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) : 95 - 95
  • [2] Signaling through JAK2-STAT5 pathway is essential for IL-3-Induced activation of microglia
    Bright, JJ
    Natarajan, C
    Sriram, S
    Muthian, G
    [J]. GLIA, 2004, 45 (02) : 188 - 196
  • [3] Tyrphostin AG490 blocks activation of JAK3 and rejection of heart allografts in rats
    Kirken, R
    Erwin-Cohen, R
    Behbod, F
    Wang, ME
    Ku, J
    Stepkowski, SM
    Kahan, BD
    [J]. TRANSPLANTATION, 1999, 67 (09) : S570 - S570
  • [4] Tyrphostin AG490 Agent Modestly but Significantly Prevents Onset of Type 1 in NOD Mouse; Implication of Immunologic and Metabolic Effects of a Jak-Stat Pathway Inhibitor
    Abdoreza Davoodi-Semiromi
    Azadeh Hassanzadeh
    Clive H. Wasserfall
    Andrew Droney
    Mark Atkinson
    [J]. Journal of Clinical Immunology, 2012, 32 : 1038 - 1047
  • [5] Tyrphostin AG490 Agent Modestly but Significantly Prevents Onset of Type 1 in NOD Mouse; Implication of Immunologic and Metabolic Effects of a Jak-Stat Pathway Inhibitor
    Davoodi-Semiromi, Abdoreza
    Hassanzadeh, Azadeh
    Wasserfall, Clive H.
    Droney, Andrew
    Atkinson, Mark
    [J]. JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 (05) : 1038 - 1047
  • [6] PPARγ agonists inhibit IFNγ-induced activation of JAK-STAT pathway in microglia
    Muthian, G
    Raikwar, HP
    Rajasingh, J
    Johnson, C
    Bright, JJ
    [J]. FASEB JOURNAL, 2005, 19 (04): : A957 - A957
  • [7] TGF-β inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes
    Bright, JJ
    Sriram, S
    [J]. JOURNAL OF IMMUNOLOGY, 1998, 161 (04): : 1772 - 1777
  • [8] JAK-2 inhibitor tyrphostin AG490 inhibits IL-6 dependent proliferation of a myeloma cell line.
    Burger, R
    Piekorz, R
    Hocke, G
    Gramatzki, M
    [J]. BLOOD, 1997, 90 (10) : 2342 - 2342
  • [9] Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
    Nielsen, M
    Kaltoft, K
    Nordahl, M
    Ropke, C
    Geisler, C
    Mustelin, T
    Dobson, P
    Svejgaard, A
    Odum, N
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (13) : 6764 - 6769
  • [10] Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
    Nielsen, M.
    Kaltoft, K.
    Nordahl, M.
    Roepke, C.
    [J]. Proceedings of the National Academy of Sciences of the United States of America, 94 (13):