Antithrombotic Activity of a New Hypoglycemic Compound Limiglidole in Mouse Model of Cell Thrombosis

被引：2
|
作者：
Kucheryavenko, A. F. [1 ]
Spasov, A. A. [1 ]
Smirnov, A. V. [2 ]
机构：
[1] Volgograd State Med Univ, Dept Pharmacol, Volgograd, Russia
[2] Volgograd State Med Univ, Dept Pathol Anat, Volgograd, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2015年 / 159卷 / 01期
关键词：
antithrombotic activity; thrombosis; platelet aggregation; limiglidole; acetylsalicylic acid; IN-VIVO; COMPLICATIONS;
D O I：
10.1007/s10517-015-2885-x
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Antithrombotic activity of hypoglycemic compound limiglidole that exhibits antiplatelet activity 2-fold exceeded activity of antiplatelet agent acetylsalicylic acid in the mouse model of systemic collagen-epinephrine thrombosis. Limiglidole signifi cantly reduced the relative and mean area of blood clots in the sections of mouse lungs.
引用
收藏
页码：41 / 43
页数：3
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