Cobalt-catalyzed synthesis of aryl ketones and aldehydes from redox-active esters

被引：2

作者：

Wang, Lan ^{[1
]}

Yu, Jiage ^{[1
]}

Duan, Zeqing ^{[1
]}

Jin, Jingrong ^{[1
]}

Zhang, Yunfei ^{[1
]}

机构：

[1] China Agr Univ, Dept Chem, Beijing 100193, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2022年 / 20卷 / 33期

关键词：

N-HYDROXYPHTHALIMIDE ESTERS; OXIDATIVE DECARBOXYLATION; CARBOXYLIC-ACIDS; PHENYLACETIC ACIDS; MERGING PHOTOREDOX; EFFICIENT; FUNCTIONALIZATION; BIOMASS; OLEFINS; LIGHT;

D O I：

10.1039/d2ob01275h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cobalt-catalyzed decarboxylative oxidation of benzylic redox-active esters is described. This protocol efficiently converts secondary or primary aliphatic carboxylic acids into aromatic ketones or aldehydes. A wide range of substrates selectively reacted in good to excellent yields with broad functional group tolerance. Notably, various biologically active molecules could also work well, which indicated the synthetic application of such a methodology.

引用

页码：6554 / 6557

页数：4

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