A near-infrared fluorescent probe for rapid, colorimetric and ratiometric detection of bisulfite in food, serum, and living cells

被引:119
|
作者
Zhang, Qiong [1 ]
Zhang, Yi [1 ]
Ding, Shuangshuang [1 ]
Zhang, Haiyan [2 ]
Feng, Guoqiang [1 ]
机构
[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China
[2] Wuhan Polytech Univ, Sch Chem & Environm Engn, Wuhan 430023, Peoples R China
基金
中国国家自然科学基金;
关键词
Near-infrared fluorescent probe; Colorimetric; Ratiometric; Bisulfite; Bioimaging; HIGH SELECTIVITY; C=N ISOMERIZATION; AQUEOUS-SOLUTION; SO2; DERIVATIVES; SULFUR-DIOXIDE; FAR-RED; SULFITE; HYBRID; WATER; SENSITIVITY;
D O I
10.1016/j.snb.2015.01.122
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A new near-infrared fluorescent probe was developed for rapid, colorimetric and ratiometric fluorescent detection of bisulfite and sulfite anions. This probe is based on a conjugated coumarinindolium system, which was found to show rapid response, high selectivity and sensitivity for bisulfite/sulfite anions with significant dual colorimetric and ratiometric fluorescent signal changes in aqueous solution under mild conditions. The detection limit of this probe for bisulfite was found to be as low as 27 nM. The applications of this probe for bisulfite detection in real food samples and serum samples, and bioimaging of bisulfite in living cells were all successfully investigated. Besides, a simple dipstick-based test system was also developed with this probe for rapid detection of bisulfite. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:377 / 384
页数:8
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