ESIPT-based fluorescence probe for the rapid detection of peroxynitrite 'AND' biological thiols

被引：62
|
作者：
Wu, Luling [1 ]
Han, Hai-Hao [2 ]
Liu, Liyuan [1 ]
Gardiner, Jordan E. [1 ]
Sedgwick, Adam C. [1 ,3 ]
Huang, Chusen [4 ,5 ]
Bull, Steven D. [1 ]
He, Xiao-Peng [2 ]
James, Tony D. [1 ]
机构：
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
[2] East China Univ Sci & Technol, Sch Chem & Mol Engn, Feringa Nobel Prize Scientist Joint Res Ctr, Key Lab Adv Mat & Joint Int Res,Lab Precis Chem &, 130 Meilong Rd, Shanghai 200237, Peoples R China
[3] Univ Texas Austin, Dept Chem, 105 E 24th St A5300, Austin, TX 78712 USA
[4] Shanghai Normal Univ, Shanghai Key Lab Rare Earth Funct Mat, Educ Minist, Key Lab Resource Chem, 100 Guilin Rd, Shanghai 200234, Peoples R China
[5] Shanghai Normal Univ, Shanghai Municipal Educ Comm Key Lab Mol Imaging, Dept Chem, 100 Guilin Rd, Shanghai 200234, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 80期
关键词：
NITRIC-OXIDE; REDOX REGULATION; REACTIVE OXYGEN; RECENT PROGRESS; GLUTATHIONE; DISEASE; STATE; LUMINESCENT; NITRATION; HEALTH;
D O I：
10.1039/c8cc06917d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An ESIPT-based 'AND' logic fluorescence probe (GSH-ABAH) was developed for the simultaneous detection of ONOO- and biological thiols. GSH-ABAH was shown to have good cell permeability and with the addition of just SIN-1 (ONOO- donor) or GSH, no fluorescence response was observed in live cells. However, in the presence of both analytes GSH-ABAH could be used to image exogenous ONOO- 'AND' GSH added to RAW264.7 cells.
引用
收藏
页码：11336 / 11339
页数：4
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