Expectant management in di-chorionic pregnancies complicated by discordant anomalous twin

被引:3
|
作者
Algeri, Paola [1 ]
Russo, Francesca M. [1 ]
Incerti, Maddalena [1 ]
Cozzolino, Sabrina [1 ]
Pelizzoni, Francesca [1 ]
Bernasconi, Davido R. [2 ]
Montanelli, Luca [1 ]
Locatelli, Luca [1 ]
Vergani, Patrizia [1 ]
机构
[1] Univ Milano Bicocca, Dept Obstet & Gynecol, MBBM Fdn, S Gerardo Hosp, Via Pergolesi 33, I-20900 Monza, Monza E Brianza, Italy
[2] Univ Milano Bicocca, Sch Med & Surg, Ctr Biostat Clin Epidemiol, Monza, Monza E Brianza, Italy
关键词
Discordant malformation; expectant management; twin pregnancy; SELECTIVE TERMINATION; PERINATAL OUTCOMES; CONGENITAL-ANOMALIES; MULTIPLE BIRTHS; FETAL ANOMALIES; FETUS; TRENDS;
D O I
10.1515/jpm-2017-0032
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Fetal malformations are more frequent in twins than in singletons. The aim of our study was to define the influence of a malformed twin on di-chorionic pregnancy outcomes. We performed a retrospective cohort study of di-chorionic pregnancies delivered between 2000 and 2015. Exclusion criteria were: both twins affected by fetal malformations, double intra-uterine fetal death in pregnancies without fetal malformation, selective feticide and therapeutic pregnancy termination. We compared maternal and fetal outcomes of di-chorionic pregnancies not complicated by fetal malformations with pregnancies affected by a single malformed fetus with conservative management. We included 642 di-chorionic pregnancies: 56 (case group, 8.7%) with one twin affected by a malformation (20 minor, 36 major ones), 586 (control group, 91.3%) without fetal malformation. No differences were found on maternal and not malformed co-twin outcomes when compared to pregnancies with no malformation; case vs control group presented similar rates of preeclampsia (8.9% vs. 10.8%, respectively), intrauterine growth restriction (7.1% vs. 9.4%) and composite adverse neonatal outcomes (19.6% vs. 15.1%). No case of fetal death in not malformed co-twin was reported. Expectant management could be a safe option for both mother and co-twin in case of di-chorionic twin pregnancy complicated by only one malformed fetus.
引用
收藏
页码:721 / 727
页数:7
相关论文
共 38 条
  • [1] EXPECTANT MANAGEMENT OF TWIN PREGNANCIES DISCORDANT FOR ANENCEPHALY
    LIPITZ, S
    MEIZNER, I
    YAGEL, S
    SHAPIRO, I
    ACHIRON, R
    SCHIFF, E
    [J]. OBSTETRICS AND GYNECOLOGY, 1995, 86 (06): : 969 - 972
  • [2] Expectant Management in Twin Pregnancies With Discordant Structural Fetal Anomalies
    Linskens, Ingeborg H.
    van Elburg, Ruurd M.
    Oepkes, Dick
    van Vugt, John M. G.
    Haak, Monique C.
    [J]. TWIN RESEARCH AND HUMAN GENETICS, 2011, 14 (03) : 283 - 289
  • [3] Twin pregnancies complicated by intrauterine death of one co-twin: Maternal risks of expectant management
    Hruby, E
    [J]. RECENT ADVANCES IN PRENATAL GENETIC DIAGNOSIS, 2004, : 183 - 186
  • [4] Results of expectant management in singleton and twin pregnancies complicated by preterm premature rupture of membranes
    Kacperczyk-Bartnik, Joanna
    Bartnik, Pawel
    Teliga-Czajkowska, Justyna
    Malinowska-Polubiec, Aneta
    Dobrowolska-Redo, Agnieszka
    Romejko-Wolniewicz, Ewa
    Rudzinski, Patryk
    Czajkowski, Krzysztof
    [J]. GINEKOLOGIA POLSKA, 2022, 93 (12) : 999 - 1005
  • [5] Management of twin pregnancies discordant for anencephaly
    Sebire, NJ
    Sepulveda, W
    Hughes, KS
    Noble, P
    Nicolaides, KH
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1997, 104 (02): : 216 - 219
  • [6] Management of Complicated Monochorionic Twin Pregnancies
    Degenhardt, J.
    Enzensberger, C.
    Tenzer, A.
    Kawecki, A.
    Kohl, T.
    Axt-Fliedner, R.
    [J]. ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, 2015, 219 (01): : 22 - 27
  • [7] FETOSCOPY IN THE MANAGEMENT OF TWIN PREGNANCIES DISCORDANT FOR A SEVERE ABNORMALITY
    RODECK, CH
    [J]. ACTA GENETICAE MEDICAE ET GEMELLOLOGIAE, 1984, 33 (01): : 57 - 60
  • [8] The risk of perinatal mortality by week of expectant management in pregnancies complicated by diabetes
    McElwee, Eliza R.
    Oliver, Emily A.
    Austin, Brittany
    Haney, Ashley
    Cuff, Ryan
    Head, Barbara
    Karanchi, Harsha
    Loftley, Aundrea
    Finneran, Matthew M.
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2021, 224 (02) : S603 - S604
  • [9] Expectant management of tubal pregnancies with human chorionic gonadotropin up to 2000 mIU/mL
    Kugelman, Nir
    Cohen, Bracha
    Yossef, Fayrooz
    Margieh, Nadine
    Regev, Noam
    Shani, Uria
    Bart, Yossi
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2024, 164 (03) : 1094 - 1100
  • [10] Twin pregnancies discordant for anencephaly - management, pregnancy outcome and review of literature
    Leeker, M
    Beinder, E
    [J]. EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2004, 114 (01) : 15 - 18