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- [10] Long-term Safety and Efficacy of Tezacaftor/Ivacaftor in Patients With Cystic Fibrosis Homozygous for F508del-CFTR or Heterozygous for F508del and a Residual Function Mutation: First Interim Analysis Results of a Phase 3, Open-label, Rollover Study AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197