Synthesis of 3-(1-aminoethyl)adamantan-1-ol by hydroxylation of 1-(1-adamantyl)ethanamine hydrochloride (rimantadine)

被引：0
|
作者：
Khusnutdinov, R. I. [1 ]
Shchadneva, N. A. [1 ]
Khisamova, L. F. [1 ]
Dzhemilev, U. M. [1 ]
机构：
[1] Russian Acad Sci, Inst Petrochem & Catalysis, Ufa 450075, Bashkortostan, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 51卷 / 01期
关键词：
ADAMANTANE;
D O I：
10.1134/S1070428015010042
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A procedure has been developed for the selective synthesis of 3-(1-aminoethyl)adamantan-1-ol by hydroxylation of 1-(1-adamantyl)ethanamine hydrochloride with the system H2O-CBrCl3 in the presence of W(CO)(6) activated by pyridine.
引用
收藏
页码：22 / 25
页数：4
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