Cancer mortality study among French cement production workers

被引:10
|
作者
Dab, William [1 ]
Rossignol, Michel [2 ,3 ]
Luce, Daniele [4 ]
Benichou, Jacques [5 ,6 ]
Marconi, Alain [7 ]
Clement, Philippe [8 ]
Aubier, Michel [9 ,10 ]
Zmirou-Navier, Denis [11 ,12 ,13 ]
Abenhaim, Lucien [14 ,15 ]
机构
[1] Conservatoire Natl Arts & Metiers, Hyg & Safety Dept, French Natl Inst Sci Technol & Management, F-75003 Paris, France
[2] McGill Univ, Dept Epidemiol Biostat & Occupat Hlth, Montreal, PQ, Canada
[3] LASER Ctr Risk Res, Montreal, PQ, Canada
[4] INSERM, U687, Villejuif, France
[5] Rouen Univ Hosp, Dept Biostat, Rouen, France
[6] INSERM, Unit U657, Rouen, France
[7] Ciments Lafarge, St Cloud, France
[8] Ciments Calcia, Guerville, France
[9] Hop Xavier Bichat, Dept Pneumol, Paris, France
[10] INSERM, Unit U700, Paris, France
[11] Nancy Univ, Sch Med, INSERM, Unit U954, Nancy, France
[12] EHESP Sch Publ Hlth, Rennes, France
[13] EHESP Sch Publ Hlth, Paris, France
[14] London Sch Hyg & Trop Med, London WC1, England
[15] LASER UK, London, England
关键词
Mortality study; Cohort study; Cement production; Portland cement; Cancer; LUNG-CANCER; DEATH CERTIFICATE; OCCUPATIONAL RISK; UNITED-STATES; INDUSTRY; EXPOSURES; MASONS; COLON; DUST; MEN;
D O I
10.1007/s00420-010-0530-6
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
To analyse the mortality and its causes, especially cancer, among French cement production workers. A cohort of all workers employed at least 1 year in one of the main four cement companies in France was assembled (9,118 workers, 122,124 person-years of follow-up between 1990 and 2005). A common job titles classification was used to analyse occupational risk factors. We conducted a standardized mortality ratio analysis based on age, gender and calendar-period-specific national mortality rates and explored the combined effect of job titles and duration through an internal Cox regression analysis. The number of deaths during the follow-up period was 430 (4.7%). Malignant neoplasm was the cause of 48.1% of deaths. Overall, a deficit in all-causes mortality (standardized mortality ratio (SMR): 0.68, 95% confidence interval (CI) 0.61-0.74) and in cancer mortality (SMR: 0.80, CI 0.69-0.92) was observed. Working in the quarry, yard and shipping sectors was associated with a 50% higher all-causes mortality risk in comparison with the administrative sector. This cohort study does not support previous observations that cement workers are at higher risk of cancer mortality than the general population. The length of follow-up should be increased, and specific exposures deserve analysis.
引用
收藏
页码:167 / 173
页数:7
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