Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe

被引:30
|
作者
Sapozhnikova, Veronika V. [1 ]
Kuranov, Roman V. [1 ]
Cicenaite, Inga [1 ]
Esenaliev, Rinat O. [1 ]
Prough, Donald S. [1 ]
机构
[1] Univ Texas Med Branch, Ctr Biomed Engn, Lab Opt Sensing & Monitoring, Dept Neurosci & Cell Biol,Dept Anesthesiol, Galveston, TX 77555 USA
关键词
noninvasive monitoring; glucose; tissue; pressure; optical coherence tomography;
D O I
10.1117/1.2909671
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by the OCT probe. We studied the influence of high (> 10 kPa) and low (<1 kPa) pressure levels on OCT blood glucose monitoring. We showed that controlling external pressure to <1 kPa substantially improved the accuracy and reproducibility of OCT-based glucose monitoring. (C) 2008 Society of Photo-Optical Instrumentation Engineers.
引用
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页数:4
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