Can we utilize photorefractive keratectomy to improve visual acuity in adult amblyopic eyes?

Purpose: To report the results of photorefractive keratectomy (PRK) in adult amblyopic patients. Design: Noncomparative case series. Participants: Thirty-eight amblyopic eyes of 36 adult patients who had undergone PRK ranging from -14.63 diopters (D) to +3.75 D (mean, -6.38 +/- 4.10) were analyzed. Methods: Preoperative and postoperative (1, 3, and 6 months) refractions and measurements of the best spectacle-corrected visual acuity (BSCVA) were reviewed. Statistical evaluation was performed using a paired Student's t test. Main Outcome Measures: Best-corrected visual acuity before and after PRK Results: Before PRK, BSCVA ranged between 0.2 and 0.7 lines (mean, 0.60 +/- 0.13). One month after PRK, BSCVA ranged between 0.2 and 1.2 lines (mean, 0.77 +/- 0.24), with a significant difference (P = 3X10(-5)). Three months after PRK, BSCVA ranged between 0.15 and 1.15 lines (mean, 0.84 +/- 0.23), with a significant difference (P = 5X10(-7)). Six months after PRK, BSCVA ranged between 0.25 and 1.3 lines (mean, 0.88 +/- 0.25), with a significant difference (P = 8X10(-8)). Conclusions: Our study does not imply that refractive surgery should or maybe performed in young children but, rather, that adults wishing to undergo refractive surgery may undertake such procedures despite an amblyopic eye thought to be refractory to visual rehabilitation by conventional methods, such as spectacles and contact lenses.