Rats in the genomic era

被引:13
|
作者
Worley, K. C. [1 ]
Weinstock, G. M. [1 ]
Gibbs, R. A. [1 ]
机构
[1] Baylor Coll Med, Human Genome Sequencing Ctr, Dept Mol & Human Genet, Houston, TX 77030 USA
关键词
Rattus norvegicus; genome sequence; single nucleotide polymorphisms; haplotype map; finished sequence;
D O I
10.1152/physiolgenomics.00208.2007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The rat genome project and the resources that it has generated are transforming the translation of rat biology to human medicine. The rat genome was sequenced to a high quality "draft," the structure and location of the genes were predicted, and a global assessment was published (Gibbs RA et al., Nature 428: 493-521, 2004). Since that time, researchers have made use of the genome sequence and annotations and related resources. We take this opportunity to review the currently available rat genome resources and to discuss the progress and future plans for the rat genome.
引用
收藏
页码:273 / 282
页数:10
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