Engineering a DNA damage response without DNA damage

被引：3
|
作者：
Yeung, ManTek [1 ,2 ]
Durocher, Daniel [1 ,2 ]
机构：
[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
[2] Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada
来源：
GENOME BIOLOGY | 2008年 / 9卷 / 07期
关键词：
D O I：
10.1186/gb-2008-9-7-227
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Recent work has achieved the feat of activating the DNA damage checkpoint in the absence of DNA damage, revealing the importance of protein-chromatin associations for the activation, amplification and maintenance of the DNA damage response.
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页数：4
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