Effect of prenatal aluminium lactate exposure on conditioned taste aversion and passive avoidance task in the rat

被引：0
|
作者：
Gonda, Z
Lehotzky, K
机构：
[1] NATL INST OCCUPAT HLTH, DEPT TOXICOL, H-1450 BUDAPEST, HUNGARY
[2] EOTVOS LORAND UNIV, DEPT COMPARAT PHYSIOL, BUDAPEST, HUNGARY
来源：
JOURNAL OF APPLIED TOXICOLOGY | 1996年 / 16卷 / 06期
关键词：
aluminium; gestational exposure; taste aversion; passive avoidance learning; rat offspring;
D O I：
10.1002/(SICI)1099-1263(199611)16:6<529::AID-JAT392>3.0.CO;2-S
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Pregnant SPRD rats were injected s.c. daily with 2.45, 4.9 and 9.8 mg kg(-1) aluminium lactate or distilled water on gestational days 7-15, Gestational aluminium treatment had no effect either on litter size or the body weight of pups on postnatal day 1 but it decreased postnatal weight gain resulting in significantly lower body weight at weaning (postnatal day 22), It had no effect on the acquisition of a conditioned taste aversion, but in a passive avoidance task the learning ability of pups of dams given the top dose of aluminium was impaired.
引用
收藏
页码：529 / 532
页数：4
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