The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review

被引：6

作者：

Ratajczyk, Krzysztof ^{[1
]}

Konieczny, Andrzej ^{[2
]}

Czekaj, Adrian ^{[1
]}

Piotrow, Pawel ^{[1
]}

Fiutowski, Marek ^{[1
]}

Krakowska, Kornelia ^{[2
]}

Kowal, Pawel ^{[1
]}

Witkiewicz, Wojciech ^{[3
]}

Marek-Bukowiec, Karolina ^{[3
]}

机构：

[1] Reg Specialist Hosp Wroclaw, Dept Urol, Kamienskiego 73a, PL-51124 Wroclaw, Poland

[2] Wroclaw Med Univ, Dept Nephrol & Transplantat Med, Borowska 213, PL-50556 Wroclaw, Poland

[3] Reg Specialist Hosp Wroclaw, Ctr Res & Dev, Kamienskiego 73a, PL-51124 Wroclaw, Poland

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2022年 / 19卷 / 16期

关键词：

urinary RBP4; renal diseases; biomarker; CHRONIC KIDNEY-DISEASE; RENAL-CELL CARCINOMA; HEALTHY-CHILDREN; VITAMIN-A; BIOMARKERS; DIAGNOSIS; INJURY; DYSFUNCTION; EXCRETION; TRANSPORT;

D O I：

10.3390/ijerph19169878

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force. Here, we summarize the most important existing data on the associations between urinary retinol-binding protein 4 and renal diseases and highlight the untapped potential of retinol-binding protein 4 in clinical use.

引用

页数：13

共 50 条

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