Multifunctional ZnO/SiO2 Core/Shell Nanoparticles for Bioimaging and Drug Delivery Application

被引：28

作者：

Prasanna, A. P. S. ^{[1
]}

Venkataprasanna, K. S. ^{[1
]}

Pannerselvam, Balashanmugam ^{[2
]}

Asokan, Vijayshankar ^{[3
]}

Jeniffer, R. Sofia ^{[4
]}

Venkatasubbu, G. Devanand ^{[1
]}

机构：

[1] SRM Inst Sci & Technol, Dept Phys & Nanotechnol, Kattankulathur 603203, Tamil Nadu, India

[2] Anna Univ, Ctr Nanosci & Technol, Chennai, Tamil Nadu, India

[3] Chalmers Univ, Dept Chem & Chem Engn, Gothenburg, Sweden

[4] VIT Univ, Ctr Nanotechnol Res CNR, Vellore, Tamil Nadu, India

来源：

JOURNAL OF FLUORESCENCE | 2020年 / 30卷 / 05期

关键词：

Bioimaging; Core/shell; Sustainable drug release; Biocompatible; ZNO NANOPARTICLES; QUANTUM DOTS; FABRICATION; CURCUMIN;

D O I：

10.1007/s10895-020-02578-z

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Semiconducting nanoparticles with luminescent properties are used as detection probes and drug carriers in in-vitro and in-vivo analysis. ZnO nanoparticles, due to its biocompatibility and low cost, have shown potential application in bioimaging and drug delivery. Thus, ZnO/SiO2 core/shell nanoparticle was synthesised by wet chemical method for fluorescent probing and drug delivery application. The synthesised core/shell nanomaterial was characterized using XRD, FTIR, UV-VIS spectroscopy, Raman spectroscopy, TEM and PL analysis. The silicon shell enhances the photoluminescence and aqueous stability of the pure ZnO nanoparticles. The porous surface of the shell acts as a carrier for sustained release of curcumin. The synthesized core/shell particle shows high cell viability, hemocompatibility and promising florescent property.

引用

页码：1075 / 1083

页数：9

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