Promises of Lipid-based Drug Delivery Systems in the Management of Breast Cancer

被引:5
|
作者
Thotakura, Nagarani [1 ]
Gupta, Madan M. [2 ]
Rajawat, Jitendra S. [3 ]
Raza, Kaisar [1 ]
机构
[1] Cent Univ Rajasthan, Sch Chem Sci & Pharm, Dept Pharm, Bandarsindri 305817, Rajasthan, India
[2] Univ West Indies, Sch Pharm, Fac Med Sci, St Augustine, Trinidad Tobago
[3] BN Univ, BN Coll Pharm, Udaipur, Rajasthan, India
关键词
Liposomes; lipospheres; lipid polymer hybrid nanoparticles; nanostructured lipid carriers; solid lipid nanoparticles; tumor; POLYMER HYBRID NANOPARTICLES; IN-VITRO CYTOTOXICITY; LIPOSOMAL DOXORUBICIN; THERAPEUTIC DELIVERY; CARRIERS; FORMULATION; CELLS; PLATFORM; NANOMEDICINE; MCF7;
D O I
10.2174/1381612827666210728104318
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Breast cancer is one of the leading types among the common non-cutaneous malignancies in women. All the curative methods available for its treatment are minimal due to their toxicity issues and dose-related side effects. Various evolving nanotechnology techniques displayed the opportunity to target breast cancer. One such delivery system is lipid-based drug delivery systems (LDDS). This concept is constrained only for the laboratory scale should be shifted to the industrial level targeting the nanomedicine with clinical benefits. This work tried to portray the advancements in the LDDS along with the lipid-based excipients, advantages, disadvantages and applications. It even helped in highlighting the recently developed lipid-based nanocarriers for breast cancer management.
引用
收藏
页码:4568 / 4577
页数:10
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