Step-up vs top-down therapy for Crohn's disease: medicine vs surgery

被引：15
|
作者：
Shen, Bo [1 ]
机构：
[1] Cleveland Clin Fdn, Ctr Inflammatory Bowel Dis, Digest Dis & Surg Inst, 9500 Euclid Ave, Cleveland, OH 44195 USA
来源：
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY | 2017年 / 14卷 / 12期
关键词：
EARLY COMBINED IMMUNOSUPPRESSION; MANAGEMENT; COLITIS; TRIAL;
D O I：
10.1038/nrgastro.2017.139
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Ileocaecal resection has traditionally been reserved for the treatment of biologic-refractory inflammatory, fibrostenotic or fistulizing Crohn's disease of the terminal ileum. Now, for the first time, this surgical approach has been investigated as an initial treatment for steroid or immunomodulator-refractory Crohn's ileitis, in comparison with anti-TNF therapy.
引用
收藏
页码：693 / 694
页数：2
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