Learning about human population history from ancient and modern genomes

被引:96
|
作者
Stoneking, Mark [1 ]
Krause, Johannes [2 ]
机构
[1] Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany
[2] Univ Tubingen, Inst Archaeol Sci, D-72074 Tubingen, Germany
关键词
MITOCHONDRIAL-DNA; Y-CHROMOSOME; NEANDERTHAL GENOME; MOLECULAR-CLONING; GENETIC DIVERSITY; WIDE PATTERNS; SEQUENCE; ADMIXTURE; MTDNA; ORIGIN;
D O I
10.1038/nrg3029
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Genome-wide data, both from SNP arrays and from complete genome sequencing, are becoming increasingly abundant and are now even available from extinct hominins. These data are providing new insights into population history; in particular, when combined with model-based analytical approaches, genome-wide data allow direct testing of hypotheses about population history. For example, genome-wide data from both contemporary populations and extinct hominins strongly support a single dispersal of modern humans from Africa, followed by two archaic admixture events: one with Neanderthals somewhere outside Africa and a second with Denisovans that (so far) has only been detected in New Guinea. These new developments promise to reveal new stories about human population history, without having to resort to storytelling.
引用
收藏
页码:603 / 614
页数:12
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