Genetics of melanoma tumorigenesis

被引：32
|
作者：
Singh, M. [1 ]
Lin, J. [1 ]
Hocker, T. L.
Tsao, H. [2 ,3 ,4 ]
机构：
[1] Harvard Med Sch, Dept Dermatol, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[4] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA
来源：
BRITISH JOURNAL OF DERMATOLOGY | 2008年 / 158卷 / 01期
关键词：
genetics; melanoma; therapy;
D O I：
10.1111/j.1365-2133.2007.08316.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Melanoma therapy is moving away from combinatorial approaches and towards newer targeted strategies. With the identification of mutations in various RAS pathway genes, there are now tremendous opportunities to bring inhibitors of RAS signalling to the clinical arena.
引用
收藏
页码：15 / 21
页数：7
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