An exploratory study of depot-medroxyprogesterone acetate and bone mineral density in adolescent and young adult women with cerebral palsy

被引：2

作者：

Roden, R. Claire ^{[1
]}

Noritz, Garey ^{[2
,3
]}

McKnight, Erin R. ^{[1
,2
]}

Bonny, Andrea E. ^{[1
,2
,4
]}

机构：

[1] Nationwide Childrens Hosp, Div Adolescent Med, 700 Childrens Dr, Columbus, OH 43205 USA

[2] Ohio State Univ, Coll Med, 370 W 9th Ave, Columbus, OH 43210 USA

[3] Nationwide Childrens Hosp, Div Complex Care, 700 Childrens Dr, Columbus, OH 43205 USA

[4] Nationwide Childrens Hosp, Res Inst, Ctr Clin & Translat Res, 700 Childrens Dr, Columbus, OH 43205 USA

来源：

CONTRACEPTION | 2020年 / 101卷 / 04期

关键词：

Adolescence; Bone mineral density; Disability; Contraception; Depot medroxyprogesterone acetate; Cerebral palsy; CHILDREN; DISABILITY;

D O I：

10.1016/j.contraception.2019.12.009

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To explore whether use of depot-medroxyprogesterone acetate (DMPA) in adolescent and young adult females with cerebral palsy is associated with lower bone mineral density (BMD). Methods: A chart review of adolescent and young adult females with cerebral palsy who had undergone dual-energy X-ray absorptiometry, comparing BMD among those with (n = 19) and without DMPA (n = 84) exposure. Results: BMD was similar in patients with and without DMPA exposure. All patients had low BMD, with average Z-scores of less than -2 at most sites. Conclusion: Results suggest that DMPA is not associated with lower BMD in non-ambulatory adolescent and young adult females with cerebral palsy. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：273 / 275

页数：3

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