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Solid-State Ion-Selective Electrode with an Ion - Electron Transducer for Doxycycline Determination

被引：2
|
作者：
Ryasenskii, S. S. [1 ]
Feofanova, M. A. [1 ]
Vasil'eva, D. V. [1 ]
Mantrov, G. I. [1 ]
机构：
[1] Tver State Univ, Tver 170100, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2016年 / 50卷 / 03期
关键词：
ion-selective electrode; polyaniline; ion - electron transducer;
D O I：
10.1007/s11094-016-1424-z
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A solid-state ion-selective electrode (ISE) for doxycycline hydrochloride determination is proposed. A construction feature is a plasticized membrane ion-electron transducer containing polyaniline. The transducer is situated between the current conductor and ion-selective membrane. The main metrological characteristics of the electrode are determined. It is established that the transducer increases the stability of the electrode potential during the measurements. It is demonstrated that the ISE can be used in practice for quantitative determination of doxycycline hydrochloride in dosage forms.
引用
收藏
页码：205 / 208
页数：4
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