Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis

被引：28
|
作者：
Namelikonda, Niranjan Kumar [1 ]
Manetsch, Roman [1 ]
机构：
[1] Univ S Florida, Dept Chem, Tampa, FL 33620 USA
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 10期
关键词：
FAMILY PROTEINS; THIO ACIDS; AZIDES; DISCOVERY; CHEMISTRY; MECHANISM; AMIDATION; DESIGN; ALKYNE;
D O I：
10.1039/c1cc14724b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides.
引用
收藏
页码：1526 / 1528
页数：3
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