For 40 years, international rules have limited human embryo research to the first 14 days of embryonic development. On May 26, 2021, in its latest guidelines for stem cell research and its medical applications, the International Society for Stem Cell Research eased the 14-day restriction. This raises myriad ethical issues. At their core is the debate over the moral status of embryos, which exposes ethical conflicts between cultural perspectives. This article discusses the moral status of embryos and argues from the perspective of Confucian ethics that the 14-day limit should not be waived at the present moment.