ANTIMICROBIAL ACTIVITY AND CELLULAR TOXICITY OF FLAVONOID EXTRACTS FROM PONGAMIA PINNATA AND VITEX NEGUNDO

被引:0
|
作者
Sharma, Amit [2 ]
Tyagi, Sapna [1 ]
Nag, Ruchi [1 ]
Chaturvedi, Arjit [1 ]
Nag, T. N. [1 ]
机构
[1] MGS Univ, MN Inst Appl Sci, Plant Tissue Culture & Biotechnol Lab, Bikaner 334022, Rajasthan, India
[2] MGS Univ, MN Inst Appl Sci, Microbiol Lab, Bikaner 334022, Rajasthan, India
来源
ROMANIAN BIOTECHNOLOGICAL LETTERS | 2011年 / 16卷 / 04期
关键词
P; pinnata; V.negundo; flavonoids; antimicrobial activity; cellular toxicity; VITRO TISSUE-CULTURE; PLANTS; SEEDS;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Flavonoids from leaf extracts of Pongamia pinnata and leaf and seeds extracts of Vitex negundo were screened against Bacillus cereus. Escherichia coli. Mycobacterium smegmatis, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, S. epidermidis, Candida albicans and Trichoderma viride adopting disc diffusion method. Results were compared with the zone of inhibition produced by commercially available standard antibiotics. Maximum activity was observed in flavonoid extract of V. negundo leaves. The extracts were also assayed for cellular toxicity to fresh human erythrocytes and found to have no cellular toxicity.
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页码:6396 / 6400
页数:5
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