Near-haploidy in a malignant sacrococcygeal teratoma

被引：14
|
作者：
Noguera, R [1 ]
Navarro, S [1 ]
Carda, C [1 ]
Peydró-Olaya, A [1 ]
Llombart-Bosch, A [1 ]
机构：
[1] Univ Valencia, Sch Med, Dept Pathol, Valencia 46010, Spain
来源：
CANCER GENETICS AND CYTOGENETICS | 1999年 / 108卷 / 01期
关键词：
D O I：
10.1016/S0165-4608(98)00115-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cytogenetic analysis of a malignant sacrococcygeal teratoma in an adult patient revealed near-haploid (77%), near-diploid (19%), and polyploid (4%) cells. The near-haploid cells had a karyotype of 25,XX,der(5)t(5;7)(p15;p13), +7,der(9)t(6;9)(p21;q34),r(17)(p13q25). In the near-diploid and polyploid cells identical copies of the structural chromosomal changes were found. Although some of the anomalies observed appear unique to this case, a common breakpoint in chromosome 6 was previously reported as specific in a subgroup of extragonadal germ cell tumors of adults. (C) Elsevier Science Inc., 1998.
引用
收藏
页码：70 / 74
页数：5
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