Continuous Remote Patient Monitoring Shows Early Cardiovascular Changes in COVID-19 Patients

被引:5
|
作者
Eisenkraft, Arik [1 ,2 ,3 ]
Maor, Yasmin [4 ,5 ]
Constantini, Keren [6 ,7 ]
Goldstein, Nir [6 ,7 ]
Nachman, Dean [1 ,2 ,8 ]
Levy, Ran [9 ]
Halberthal, Michael [10 ,11 ]
Horowitz, Netanel A. [10 ,11 ]
Golan, Ron [12 ]
Rosenberg, Elli [13 ]
Lavon, Eitan [14 ]
Cohen, Ornit [4 ,5 ,15 ]
Shapira, Guy [5 ]
Shomron, Noam [5 ]
Ishay, Arik Ben [3 ]
Sand, Efrat [3 ]
Merin, Roei [3 ]
Fons, Meir [3 ]
Littman, Romi [3 ]
Gepner, Yftach [6 ,7 ]
机构
[1] Hebrew Univ Jerusalem, Inst Res Mil Med, Fac Med, POB 12272, IL-9112102 Jerusalem, Israel
[2] Israel Def Force Med Corps, POB 12272, IL-9112102 Jerusalem, Israel
[3] Biobeat Technol Ltd, 22 Efal St, IL-4951122 Petah Tiqwa, Israel
[4] Wolfson Med Ctr, 62 Ha Lokhamim St 62, IL-58100 Holon, Israel
[5] Tel Aviv Univ, Sackler Fac Med, POB 39040, IL-6997801 Tel Aviv, Israel
[6] Tel Aviv Univ, Sch Publ Hlth, Sackler Fac Med, Dept Epidemiol & Prevent Med, POB 39040, IL-6997801 Tel Aviv, Israel
[7] Tel Aviv Univ, Sylvan Adams Sports Inst, POB 39040, IL-6997801 Tel Aviv, Israel
[8] Hadassah Kerem Med Ctr, Inst Heart, POB 911201, IL-9112102 Jerusalem, Israel
[9] Maccabi Healthcare Serv, POB 50493, IL-68125 Tel Aviv, Israel
[10] Rambam Hlth Care Campus, POB 9602, IL-3109601 Haifa, Israel
[11] Technion, Bruce Rappaport Fac Med, POB 9649, IL-3525433 Haifa, Israel
[12] Bar Ilan Univ, Fac Med Galilee, Baruch Padeh Med Ctr Poriya, IL-1528001 Poria, Israel
[13] Ben Gurion Univ Negev, Soroka Univ Med Ctr, Internal Med A, POB 151, IL-84101 Beer Sheva, Israel
[14] Hebrew Univ Jerusalem, Kaplan Med Ctr, Fac Med, POB 1, IL-76100 Rehovot, Israel
[15] Ben Gurion Univ Negev, Fac Hlth Sci, POB 653, IL-8410501 Beer Sheva, Israel
关键词
COVID-19; cardiopulmonary parameters; high-risk population; remote patient monitoring; artificial intelligence;
D O I
10.3390/jcm10184218
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
COVID-19 exerts deleterious cardiopulmonary effects, leading to a worse prognosis in the most affected. This retrospective multi-center observational cohort study aimed to analyze the trajectories of key vitals amongst hospitalized COVID-19 patients using a chest-patch wearable providing continuous remote patient monitoring of numerous vital signs. The study was conducted in five COVID-19 isolation units. A total of 492 COVID-19 patients were included in the final analysis. Physiological parameters were measured every 15 min. More than 3 million measurements were collected including heart rate, systolic and diastolic blood pressure, cardiac output, cardiac index, systemic vascular resistance, respiratory rate, blood oxygen saturation, and body temperature. Cardiovascular deterioration appeared early after admission and in parallel with changes in the respiratory parameters, showing a significant difference in trajectories within sub-populations at high risk. Early detection of cardiovascular deterioration of COVID-19 patients is achievable when using frequent remote patient monitoring.
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页数:13
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