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Newcastle Univ, Populat Hlth Sci Inst, Newcastle Univ Ctr Canc, Sir James Spence Inst,Royal Victoria Infirm, Level 5,Queen Victoria Rd, Newcastle NE1 4LP, England Newcastle Univ, Populat Hlth Sci Inst, Newcastle Univ Ctr Canc, Sir James Spence Inst,Royal Victoria Infirm, Level 5,Queen Victoria Rd, Newcastle NE1 4LP, England