Enzymatic control of the size of DNA block copolymer nanoparticles

被引:68
|
作者
Alemdaroglu, Fikri E. [1 ]
Wang, Jie [1 ]
Boersch, Michael [2 ]
Berger, Ruediger [1 ]
Herrmann, Andreas [1 ]
机构
[1] Max Planck Inst Polymer Res, D-55128 Mainz, Germany
[2] Univ Stuttgart, Inst Phys 3, D-70550 Stuttgart, Germany
关键词
bionanotechnology; block copolymers; DNA; enzymes; nanostructures;
D O I
10.1002/anie.200703466
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) The right kind of upbringing: The size of DNA nanoparticles can be adjusted by an enzymatic reaction. By varying the incubation time of spherical nucleic acid block copolymer micelles (see picture) with a non-template-dependent DNA polymerase, the size of the nanoobjects can be gradually increased. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:974 / 976
页数:3
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