Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds

被引：210
|
作者：
Michna, S
Wu, W
Lewis, JA [1 ]
机构：
[1] Univ Illinois, Dept Mat Sci & Engn, Urbana, IL 61801 USA
[2] Univ Illinois, Chem & Biomol Engn Dept, Urbana, IL 61801 USA
来源：
BIOMATERIALS | 2005年 / 26卷 / 28期
基金：
美国国家航空航天局;
关键词：
hydroxapatite; bone tissue engineering; scaffolds; direct-write assembly;
D O I：
10.1016/j.biomaterials.2005.02.040
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Hydroxyapatite (HA) scaffolds with a 3-D periodic architecture and multiscale porosity have been fabricated by direct-write assembly. Concentrated HA inks with tailored viscoelastic properties were developed to enable the construction of Complex 3-D architectures comprised Of self-supporting cylindrical rods in a layer-by-layer patterning sequence. By controlling their lattice constant and sintering conditions, 3-D periodic HA scaffolds were produced with a bimodal pore size distribution. Mercury intrusion porosimetry (MIP) was used to determine the characteristic pore size and Volume associated with the interconnected pore channels between HA rods and the finer pores within the partially sintered HA rods. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5632 / 5639
页数：8
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