Decrease of κ-opioid receptor mRNA level in ventral tegmental area of male mice after repeated experience of aggression

被引：9
|
作者：
Goloshchapov, AV
Filipenko, ML
Bondar, NP
Kudryavtseva, NN
Van Ree, JM
机构：
[1] Univ Utrecht, Ctr Med, Rudolf Magnus Inst Neurosci, Dept Pharmacol & Anat, NL-3584 CG Utrecht, Netherlands
[2] RAS, SD, Inst Bioorgan Chem, Novosibirsk, Russia
[3] RAS, SD, Inst Cytol & Genet, Novosibirsk, Russia
来源：
MOLECULAR BRAIN RESEARCH | 2005年 / 135卷 / 1-2期
关键词：
mu-opioid receptor gene; kappa-opioid receptor gene; mRNA isoforms; nucleus accumbens; ventral tegmental area; aggression;
D O I：
10.1016/j.molbrainres.2004.11.009
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Brain opioid systems have been implicated in the regulation of social interaction, including agonistic behaviour. kappa-Opioid receptor B and C mRNA levels were decreased in the ventral tegmental area but not in the nucleus accumbens in male mice with repeated experience of social victories (winners), but not in mice after social defeats (losers) after 10 but not 20 days of confrontations. mu-Opioid receptor mRNA levels were not changed. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：290 / 292
页数：3
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