Comparative mycobacterial genomics

被引：46
|
作者：
Cole, ST [1 ]
机构：
[1] Inst Pasteur, Unite Genet Mol Bacterienne, F-75724 Paris 15, France
来源：
CURRENT OPINION IN MICROBIOLOGY | 1998年 / 1卷 / 05期
关键词：
D O I：
10.1016/S1369-5274(98)80090-8
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Genomics is providing us with a mass of information about the biochemistry, physiology and pathogenesis of Mycobacterium tuberculosis and Mycobacterium leprae. Comparison of the two genome sequences is mutually enriching and indicates that the M. leprae genome appears to have undergone shrinkage and large-scale gene inactivation, which may account for the exceptionally slow growth of this organism.
引用
收藏
页码：567 / 571
页数：5
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