The clinical utility of symptom dimensions in obsessive-compulsive disorder

被引:35
|
作者
Matsunaga, Hisato [1 ]
Hayashida, Kazuhisa
Kiriike, Nobuo
Maebayashi, Kensei
Stein, Dan J. [2 ,3 ]
机构
[1] Osaka City Univ, Dept Neuropsychiat, Sch Med, Abeno Ku, Osaka 5458585, Japan
[2] Univ Cape Town, MRC Unit Anxiety Disorders, ZA-7925 Cape Town, South Africa
[3] Mt Sinai Sch Med, Dept Psychiat, New York, NY USA
关键词
Obsessive-compulsive disorder; Symptom dimension; Yale-Brown Obsessive-Compulsive Scale (Y BOCS); Clinical utility; JAPANESE PATIENTS; SCALE; PERSONALITY; RELIABILITY; FEATURES; THERAPY; PLACEBO; TRIAL;
D O I
10.1016/j.psychres.2009.09.005
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Factor analyses in obsessive-compulsive disorder (OCD) have consistently identified several different symptom dimensions Nevertheless the clinical utility of identifying such symptom dimensions remains somewhat unclear On the basis of their principal symptoms 343 OCD patients were divided into four symptom dimension subgroups 1) contamination/washing 2) hoarding 3) symmetry/repeating and ordering and 4) forbidden thoughts/checking Clinical variables including 1-year treatment outcome were compared across these patient subgroups Most patients (74%) could distinctively be categorized as falling into a particular symptom subgroup The groups were differentially characterized by some demographic and clinical features For instance both the symmetry and hoarding groups were significantly associated with decreased global functioning and greater OCD seventy Moreover the hoarding group was significantly more likely than the others to show longer duration of Illness lower rate of marriage poor insight, and poorer outcome However about a quarter of the participants could not be classified definitively into a particular group Our findings provide partial support for the clinical utility of a simple measure of symptom dimensions in OCD In clinical settings however the limitations of such a simple measure of predominant symptom dimensions should be borne in mind and further work on their validity and utility is needed (C) 2009 Elsevier Ireland Ltd All rights reserved
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页码:25 / 29
页数:5
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