Structure of the human CFTR NBD1 domain as a homodimer: Insights and applications

被引：0
|
作者：
Atwell, Shane [1 ]
Conners, Kris [1 ]
Emtage, Spencer [1 ]
Gheyi, Tarun [1 ]
Lewis, Hal [1 ]
Lu, Frances [1 ]
Romero, Rich [1 ]
Zhao, Xun [1 ]
机构：
[1] SGX Pharmaceut, San Diego, CA 92121 USA
来源：
PEDIATRIC PULMONOLOGY | 2007年
关键词：
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
引用
收藏
页码：100 / 101
页数：2
相关论文
共 50 条
  • [1] DIRECT BINDING OF CFTR MODULATORS TO HUMAN CFTR NBD1
    Hudson, R.
    Chong, P.
    Protasevich, I. I.
    Dawson, J.
    Vernon, R.
    Ney, E.
    Bihler, H.
    An, J. L.
    Kalid, O.
    Sela-Culang, I.
    Mense, M.
    Senderowitz, H.
    Brouillette, C.
    Forman-Kay, J.
    PEDIATRIC PULMONOLOGY, 2012, 47 : 243 - 243
  • [2] A Novel Activator of ATPase Activity of NBD1 Domain of the CFTR
    Singh, Jay
    Balch, William
    PROTEIN SCIENCE, 2014, 23 : 108 - 108
  • [3] CFTR MODULATORS THAT TARGET NBD1
    Huerta, C.
    Schmidt, A.
    Harness-Brumley, C.
    Millen, L.
    Mendoza, J. L.
    Fuller, M.
    Wigley, C.
    Thomas, P. J.
    PEDIATRIC PULMONOLOGY, 2014, 49 : 241 - 241
  • [4] DIRECT BINDING OF COMPOUNDS TO HUMAN CFTR NBD1: ALLOSTERY AND THE IMPORTANCE OF DOMAIN-DOMAIN INTERACTIONS
    Hudson, Rhea
    Dawson, Jennifer E.
    Chong, P. Andrew
    Vernon, Robert
    Yang, Zengrong
    Millen, Linda
    Thomas, Philip J.
    Brouillette, Christie
    Forman-Kay, Julie
    PEDIATRIC PULMONOLOGY, 2016, 51 : 141 - 142
  • [5] FUNCTIONAL STABILIZATION OF PURIFIED HUMAN CFTR BY NBD1 MUTATIONS AND BY CONFORMATION
    Urbatsch, I. L.
    Yang, Z.
    Hildebrandt, E.
    Jiang, F.
    Aleksandrov, A.
    Khazanov, N.
    Riordan, J. R.
    Senderowitz, H.
    Brouillette, C.
    Kappes, J. C.
    PEDIATRIC PULMONOLOGY, 2018, 53 : 152 - 152
  • [6] Regulation of the nbd1/R domain of CFTR by ATP and by protein kinases.
    Cohn, JA
    Borchardt, RA
    Yu, AYR
    Kole, J
    GASTROENTEROLOGY, 1997, 112 (04) : A355 - A355
  • [7] Functional Stabilization of Purified Human CFTR by NBD1 Mutations and by Phosphatidylserine
    Urbatsch, Ina
    Yang, Zhengrong
    Hildebrandt, Ellen
    Jiang, Fan
    Zhou, Qingxian
    An, Jiangli
    Xavier, Bala M.
    Khazanov, Netaly
    Senderowitz, Hanoch
    Kappes, John C.
    Brouillette, Christie G.
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 245A - 245A
  • [8] INTERACTION OF SMALL-MOLECULE CFTR MODULATORS WITH HUMAN NBD1
    Hudson, R.
    Chong, P.
    Kolodziej, A.
    Thomas, P. J.
    Forman-Kay, J. D.
    PEDIATRIC PULMONOLOGY, 2009, : 216 - 216
  • [9] Interactions of the Wild-type and ΔF508 CFTR NBD1 domain
    Kanelis, Voula
    Hudson, Rhea P.
    Baker, Jennifer M. R.
    Thibodeau, Patrick H.
    Thomas, Philip J.
    Forman-Kay, Julie D.
    BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 2006, 84 (06): : 1081 - 1081
  • [10] Protein kinase A regulates ATP hydrolysis by the CFTR NBD1/R domain.
    Howell, LD
    Chien, L
    Cohn, JA
    GASTROENTEROLOGY, 1998, 114 (04) : A379 - A379
12345