Ammonium chloride catalysed one-pot multicomponent synthesis of 1,8-dioxo-octahydroxanthenes and N-aryl-1,8-dioxodecahydroacridines under solvent free conditions

被引：45

作者：

Banerjee, Bubun ^{[1
]}

Brahmachari, Goutam ^{[1
]}

机构：

[1] Visva Bharati, Dept Chem, Lab Nat Prod & Organ Synth, Santini Ketan 731235, W Bengal, India

来源：

JOURNAL OF CHEMICAL RESEARCH | 2014年 / 12期

关键词：

1,8-dioxo-octahydroxanthenes; N-aryl-1,8-dioxodecahydroacridines; ammonium chloride; solvent-free conditions; one-pot multi-component reactions; green protocol; EFFICIENT; DERIVATIVES;

D O I：

10.3184/174751914X14177132210020

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple, straightforward and highly efficient protocol has been developed for the one-pot multicomponent synthesis of 1,8-dioxooctahydroxanthenes from the reaction of aromatic aldehydes and dimedone, and also N-aryl-1,8-dioxodecahydroacridines from aromatic aldehydes, dimedone and aromatic amines in excellent yields using ammonium chloride as a low-cost and non-toxic eco-friendly catalyst under solvent-free conditions. The salient features of the present protocol are the operational simplicity, clean reaction profiles, excellent yields, high atom-economy, relatively short reaction-time as well as the use of inexpensive and environmentally benign catalyst.

引用

页码：745 / 750

页数：6

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